Why Are My Hormones Losing Effectiveness Over Time?

Let's address some common concerns you may experience with prolonged hormone exposure, such as with GLP-1 hormones like Semaglutide or Tirzepetide. You may find your usual dosage less effective after 6-9 months, which can be attributed to your body building a tolerance, a process called Systemic Metabolic Homeostasis.

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Here are some frequently asked questions:

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• Why am I not losing weight on my usual dose?

• Is my maintenance dose less effective now?

• Why am I feeling hungrier during the day?

 

These changes don't reflect a weakening of the hormones themselves (you have the testing data on each vial); rather, your body’s receptors tend to adapt, requiring you to adjust your approach early on.

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To help mitigate these issues and maximize your results, consider these lifestyle adjustments:

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1. Exercise Regularly: Aim for at least 300 minutes of cardio and strength training each week. This helps maintain your metabolism and is REQUIRED.

2. Time-Restricted Eating: Consume all your meals within a 6-hour window and avoid calories outside this timeframe.

3. Hydration: Drink enough water to maintain regular hydration throughout the day.

4. Whole Foods: Stick to whole foods to enhance hormone absorption and avoid processed options.

5. Limit Alcohol: Alcohol can reduce your body's ability to absorb GLP-1 effectively.

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If these guidelines are not followed, you may experience a weight plateau, decreased metabolism, and increased hunger, pressing you to increase your dosage unnecessarily.

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Refer to the "16 Weight Loss Rules" on our main landing page, which serve as a guide to avoid complications and maintain your progress. By adhering to these principles, you can continue to manage your weight even as you taper off hormones.

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Remember, the key is to view hormones as an aiding tool rather than a long-term solution. Build muscle, embrace your journey towards self-improvement, and trust in your ability to maintain your success with or without hormonal assistance. The only magic during this program is the lifestyle growth that you make, and keep along the way.

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You’ve got this!

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Warm regards,

 

The GGH team.